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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAGE
All Species:
13.03
Human Site:
S245
Identified Species:
26.06
UniProt:
Q9UQ07
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ07
NP_055041.1
419
48014
S245
D
F
P
F
K
K
G
S
G
I
P
L
L
T
T
Chimpanzee
Pan troglodytes
XP_510176
419
47983
S245
D
F
P
F
K
K
G
S
G
I
P
L
L
T
T
Rhesus Macaque
Macaca mulatta
XP_001112517
461
52662
M276
L
Q
S
Q
S
R
A
M
N
F
D
F
P
F
K
Dog
Lupus familis
XP_547985
458
51843
S285
D
F
P
F
K
K
G
S
G
I
P
L
L
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVS4
420
48046
S245
D
F
P
F
K
K
G
S
G
I
P
L
L
T
A
Rat
Rattus norvegicus
Q62726
629
70550
P243
F
I
W
P
Q
C
I
P
N
N
L
K
T
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
I136
L
K
P
Q
N
L
L
I
D
D
K
G
V
I
K
Frog
Xenopus laevis
NP_001084801
411
47114
K230
L
A
L
L
K
K
F
K
P
S
R
A
M
S
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
L146
D
T
A
G
K
I
K
L
A
D
F
G
L
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786078
440
50923
G245
Y
N
F
P
S
K
K
G
S
G
I
E
K
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
Q250
I
S
H
T
E
F
P
Q
T
R
I
A
D
L
L
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
R131
I
A
Y
C
H
S
H
R
I
L
H
R
D
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
82.6
76.6
N.A.
83.5
27.8
N.A.
N.A.
28.6
63.2
N.A.
N.A.
26.7
N.A.
N.A.
50.6
Protein Similarity:
100
99.5
85.2
81.2
N.A.
89.5
42.4
N.A.
N.A.
43.9
73.2
N.A.
N.A.
42.7
N.A.
N.A.
68.4
P-Site Identity:
100
100
0
93.3
N.A.
93.3
0
N.A.
N.A.
6.6
13.3
N.A.
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
93.3
6.6
N.A.
N.A.
13.3
26.6
N.A.
N.A.
20
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
28.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
0
9
0
9
0
0
17
0
9
17
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
0
0
0
0
0
0
9
17
9
0
17
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
9
34
9
34
0
9
9
0
0
9
9
9
0
9
9
% F
% Gly:
0
0
0
9
0
0
34
9
34
9
0
17
0
0
0
% G
% His:
0
0
9
0
9
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
17
9
0
0
0
9
9
9
9
34
17
0
0
9
9
% I
% Lys:
0
9
0
0
50
50
17
9
0
0
9
9
9
0
25
% K
% Leu:
25
0
9
9
0
9
9
9
0
9
9
34
42
34
17
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
9
0
0
0
17
9
0
0
0
0
0
% N
% Pro:
0
0
42
17
0
0
9
9
9
0
34
0
9
0
0
% P
% Gln:
0
9
0
17
9
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
9
0
9
9
9
0
0
9
% R
% Ser:
0
9
9
0
17
9
0
34
9
9
0
0
0
9
0
% S
% Thr:
0
9
0
9
0
0
0
0
9
0
0
0
9
34
17
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _